Group B Streptococcus infection

Summary of changes 

Medicines: Change is GBS urine positive antibiotic dose: amoxicillin 500mg Q8H for 5 days (was 250mg 3 times a day for 3 days); in labour second 4 hourly dose of benzylpenicillin increased from 1.2g to 1.8g

Primary references

  1. Australian Government Department of Health (2020) Pregnancy Care, Clinical Practice Guidelines, Australian Government Department of Health, Canberra, accessed 5 April 2022.

  2. Northern Territory Health (2020) Group B Streptococcal Colonisation RDPH Maternity Guideline, NTG Health, Darwin, accessed 22 July 2021.

  3. Royal Australian and New Zealand College of Obstetricians and Gynaecologists Women's Health Committee (2019) Maternal Group B Streptococcus (GBS) in Pregnancy: Screening and Management, accessed 5 April 2022.

  4. Royal College of Obstetricians and Gynaecologists (2017) 'Prevention of Early-onset Neonatal Group B Streptococcal Disease (Green-top Guideline No. 36)', British Journal of Obstetrics and Gynaecology, 124(12):e280–e305, doi:10.1111/1471-0528.14821

  5. South Australian Maternal, Neonatal and Gynaecology Community of Practice (2019) Antibiotics in the Peripartum Period, SA Perinatal Practice Guideline, accessed 30 March 2022.